Within this context, the Alaoui Museum becomes the heart of an archaeological circuit including the great cultural sites that have been arranged (Carthage, Dougga, Thuburbo Majus, and El Jem and Sbeitla amphitheatres). Thus, it acquired an international fame thanks to the wealth of its collections, especially those of Roman-African mosaics.
A change in the profile of the curator was decided after the departure of Emile Bréchot (1928-1948), the second administrative curator of the museum.

His successor, Pierre Quoniam (1948-1954), who was a former member of the French School in Rome, was chosen for his qualities as a researcher to become the scientific curator of the museum assisted by a manager. He is the initiator of the new Christian wing projects established in the old stables of the palace and the Acholla Hall which would be arranged after Tunisia’s independence in 1956.

During this post-war period, regional museums were created, especially those of Sousse and Sfax as well as certain archaeological parks such as that of Antoninus Thermae in Carthage. By virtue of decrees, they became annexes to the Alaoui Museum, thus facilitating the management and conservation of antique pieces.
Postcard books illustrating the collections of the museum were diffusing its treasures throughout the world.